None of this is dosing guidance for people
In Cartersville, a dedicated team of two medical oncologists and four advanced practice providers now delivers personalized treatment plans tailored to each patients diagnosis
25 A larger, double-blind RCT of 243 cancer patients receiving cisplatin or oxaliplatin and diagnosed with CIPN showed no significant difference in peripheral neuropathic symptoms between oral ALA 600 mg/day orally and placebo but further studies are needed to conclusively determine if ALA could benefit this subset of patients
However, the rate of improvement slowed the largest changes occurred between weeks 4-8, with weeks 8-12 representing diminishing marginal gains
Disruption of this homeostatic equilibrium can lead to dysbiosis and consequent metabolic perturbations that are increasingly implicated in the pathogenesis of chronic conditions such as cancer, cardiometabolic disorders, and IBD (187)
For average weight loss, tirzepatide leads