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10.1016/j.ijbiomac.2017.01.085 111 WangY.QinS.PenG.ChenD.HanC.MiaoC.et al (2017d)

This would be expected to result in our study sample being of lower CVD risk at baseline, along with lower absolute projected reductions in risk and estimated CVD events than that which would have been predicted had our participants more closely matched those enrolled in the STEP 1 trial

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Increases in resting heart rate have also been reported, consistent with effects seen across the GLP-1 receptor agonist class

Prescribing decisions should be individualized, grounded in a complete metabolic assessment (not just HbA1c), and aligned with the patient's goals and willingness to commit to sustained treatment