Verfahren zur Herstellung nach einem der Ansprche 1 bis 8, wobei das Spalten in Schritt 2 mit einem Reagenz durchgefhrt wird, das ein oder ein Gemisch von zwei oder mehr von TFA, PhSMe, PhOMe, EDT, H 2 O, TIS or PhOH umfasst
In a recent clinical trial, adults with obesity (without diabetes) lost an average of 20.2% of their body weight with tirzepatide as compared to 13.7% with semaglutide over 72 weeks
P., Miranda-Narvez, C
122(3): 24557 Ghirardi O, Lo Giudice P, Pisano C, et al
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The clinical evidence consistently shows that tirzepatide produces greater weight loss than semaglutide, and for patients who need to lose 20% or more of their body weight to reach a healthy range, that additional efficacy can be clinically meaningful