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A Paradigm Shift in Asthma Pathobiology These findings suggest that pseudo leukotrienes may play a previously unrecognised role in driving airway inflammation

10.3390/ijms22168820 Int

Parthasarathy U, Martinelli R, Vollmann EH, Best K, Therien AG

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Jin H, Lao YM, Zhou J, Zhang HJ, Cai ZH (2017) Simultaneous determination of 13 carotenoids by a simple C18 column-based ultra-high-pressure liquid chromatography method for carotenoid profiling in the astaxanthin-accumulating Haematococcus pluvialis

One hypothesis is that we observed a greater induction of NRF2 through liver-specific Gclc deletion as compared to KEAP1 inhibition with CDDO-me because CDDO-me is a weaker inhibitor of NRF2-KEAP1 interaction compared to the ROS generated following GSH depletion