Their use is rising rapidly, and with good reason: These medications have been shown to reduce blood sugar, improve fatty liver, GERD, sleep apnea, osteoarthritis, blood pressure, triglycerides, major adverse cardiovascular events, and even show potential benefits for conditions like alcohol use disorder (Mozaffarian et al., 2025
With regular maintenancetypically once per yearyour results can last up to two years or more
Appetite Suppression - Tirzepatide acts on specific receptors in the brain to reduce appetite and promote a feeling of fullness after meals
They can lower the risk of major cardiovascular events such as heart attack , stroke , and cardiovascular death, especially in individuals with type 2 diabetes who are at higher risk for these conditions
The implication is important: there's an asymmetry to the trade-off
Those who took Tirzepatide lost around 25%