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Many researchers report minimal regression during breaks, with cumulative improvements over multiple cycles

Gut microbiota in SLE patients Alteration of gut microbiota in SLE patients In recent years, multiple studies utilizing 16S rRNA sequencing and metagenomic sequencing technologies have revealed significant alterations in the gut microbiota of SLE patients

Noori N, Honarkar E, Goldfarb DS, Kalantar-Zadeh K, Taheri M, Shakhssalim N,

doi: 10.1211/0022357011777747 65 ZhaoDYuYZhaoZSharmaRReiterRJ

Higher activity of polyADPribosyl polymerase 1 (PARP1) and more PARylated proteins have been detected in the mitochondrial fraction than in the nucleus

Air Qual Atmos Health 4 , 7993 (2011)