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Transcriptome sequencing analysis indicated that hypoxia induced reprogramming in USCs, characterized by the upregulation of oxygen-sensing, metabolic, and HIF-1 pathways, alongside the downregulation of the Hippo signaling pathway

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There was also a 56% reduction in the ESS by the end of the trial

& Krishnan, K

PMID: 21 GrantWBAl AnoutiFBoucherBJDursunEGezen-AkDJudeEBet al