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The problem was the side effects associated, particularly with GLP-1, are what we call peak to trough: so the difference between the highest amount of drug and the lowest and then going back up again to the highest caused by this twice-a-day dosingwhich you can imagine someone bouncing around maybe two to three times, the drug at peak, then trough, causes a lot of GI distress

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An Oroboros Oxygraph-2K was used to assess the level of respiration by freshly isolated mitochondria (described above)

They are, however, a very real concern for the people who come to see him

Does GLP-1 therapy work as well for women in menopause