The type of hair loss most commonly associated with GLP-1 medications is called telogen effluvium
The GLP-1R and GIPR pathways both converge on beta cell function through incretin signaling, and retatrutide provides a tool to study the amplified incretin response that occurs when both receptors are activated simultaneously
Miscellaneous studies (for example, reporting on any psychiatric adverse outcomes) as well as ongoing and planned trials are reported in Supplementary Sections 2 and 3, respectively
One study found that four percent of Americans are taking GLP-1s, which reflects a 600 percent increase in the last five years
Since commercial patients tend to be younger and healthier than Medicare beneficiaries, early GLP-1 use is reinforcing its role as a reliable foundation for diabetes care and could be a contributing factor to rising rates of monotherapy
However, the metabolic and appetite changes can be significant and should be anticipated and managed appropriately