The SURPASS-1 trial studied the efficacy and safety of the three doses of TZP versus placebo in diabetic drug-nave patients not adequately controlled with a lifestyle mediation (diet and exercise)
Mapping the mouse brain with rs-fMRI: an optimized pipeline for functional network identification
Available at: Buonanno S, Gaggiano C, Terribili R, Cantarini L, Frediani B, Gentileschi S
Muscle wasting in the context of T2D and obesity represents not only a complication but also a driver of disease progression, contributing to diminished insulin sensitivity, reduced physical capacity and adverse outcomes [3]
De Herder, Klppel)
Central GLP-1 binds to GLP-1 receptor (GLP-1R) to exert many important effects including modulation of energy balance, cardiovascular system, learning and memory, rewarding effect of food, and thermogenesis (Trapp and Cork, 2015)