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Activation of the vascular smooth muscle GLP-1/NCX1 pathway regulates cytoplasmic Ca2+ homeostasis and improves blood pressure variability in hypertension
doi: 10.1016/j.foodchem.2014.03.120 106 YangB.DingY.GuoP.YuX.YeS.NieW.et al
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Novo Nordisk, Pfizer and other big pharma companies have just taken [the hormone] GLP-1 itself, and spent 20 years stabilising the peptide, making it druggable, so its not broken down [in the body], explains John Unitt, vice president of immunology and inflammation drug discovery at Sygnature Discovery in Nottinghamshire, UK, and a GPCR drug discovery expert
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