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Alpha-lipoic acid (ALA) is a sulfur-containing antioxidant naturally produced in the body that assists in energy metabolism and can regenerate other antioxidants including vitamins C and E, glutathione, and CoQ10

This study was conducted in accordance with the Declaration of Helsinki

Sepsis affects approximately one point seven million adults yearly

Self-assembled nanospheres mediate phototherapy and deliver CpG oligodeoxynucleotides to enhance cancer immunotherapy of breast cancer and melanoma

Research has shown that glutathione has a positive effect on the normal functioning of the immune system and prevents the development of an excessive immune response and inflammation in autoimmune diseases (6)

Animals were maintained in a 15:9 h photoperiod of daily light/dark cycles to match the natural photoperiod at the collection sites (metal halide lights, with levels maintained at 150250 mol m 2 s 1 ) and in dimmed light conditions to mimic their natural sciaphilous environment (the tanks were under a canopy of 70% light-reducing shade-cloth)