Whether glucagon counter-regulation to hypoglycemia is affected during DPP-4 inhibition in type 2 diabetes has been studied in drug-nave subjects (138), in subjects when a DPP-4 inhibition was added on to insulin therapy (139), and in elderly subjects with metformin-treated type 2 diabetes (140)
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Lifestyle, dose tolerance, sleep, alcohol intake, stress, and genetics all matter
13 Ask if the patient is experiencing, or has ever experienced, nausea and vomiting because of the GLP-1 receptor agonist therapy, and if so, document this information in the patient record
Place a clean gauze pad on the injection site and apply firm pressure for a few seconds to stop bleeding