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The right indication: are these drugs right for you

MHRA-authorised options include semaglutide (Wegovy) under NICE TA875 and tirzepatide (Mounjaro) under NICE TA1026, both available through specialist NHS weight management services for eligible patients meeting defined BMI and comorbidity criteria

For example, vitamin B12 shots for weight loss are typically administered weekly, or twice a week for fat-burning and boosting metabolism

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This adaptation timeline is consistent across clinical trials and reflects normal homeostatic adjustment rather than medication ineffectiveness