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To evaluate the ability of any one of the therapeutic agents described herein to protect SGNs or the stria vascularis, or block hair cell death or restore hair cells following cisplatin or aminoglycoside insult, the following ex vivo models are used

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Additionally, concerns regarding long-term biosafety, redox imbalance, metal accumulation, and the scalability of complex nanomaterial synthesis limit regulatory progress

Common injection sites include the abdomen (2 inches from navel), upper thighs, or upper arms