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For example, in elderly individuals, reduced microbial diversity and decreased abundance of beneficial bacteria lead to lower SCFA levels and increased intestinal permeability [170]

In such cases, the symptom may be related to ongoing gastro-oesophageal reflux or other gastrointestinal effects that do not fully resolve

Some users report accelerated improvement, while others see minimal benefit

Life-threatening events are seen when greater than 150 to 200 mg/kg of caffeine is consumed, and fatalities have been reported when 5 to 50 g of caffeine was ingested

It is involved in the synthesis of acetylcholine, a neurotransmitter crucial for memory and learning