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The body has a defense mechanism against oxidative stress in which both enzymatic and nonenzymatic molecules are the two prime components

Cell Death Dis 13(6):530 Dang R et al (2022) Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

Even the light from opening your refrigerator contributes to photodegradation over time