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Rebound or retention: A meta-analysis of weight regain after the discontinuation of glucagon-like peptide-1 (GLP-1) receptor agonists and other anti-obesity drugs

Older adults are more likely to be on multiple medications, increasing the potential for interactions

The active ingredients in these injections are carefully formulated to target fat cell membranes, causing them to break apart and release their contents

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Higher mitochondrial metabolism in the neurons result in generation of Complex I dependent hydrogen peroxide and neuronal membranes, rich in polyunsaturated fatty acids, are particularly vulnerable to oxidative stress due to their possession of unsaturated double bonds

If pancreatitis is suspected (severe, persistent abdominal pain, particularly if radiating to the back, accompanied by nausea and vomiting), the GLP-1 medication should be discontinued immediately and urgent medical assessment sought