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Generally, GLP-1 agonist medications are FDA approved for adults aged 18 years and older with certain body mass indexes (BMI) (typically a BMI of 30 or above, or a BMI of 27 or above if you have a weight-related health condition such as hypertension, high cholesterol, weight-related anxiety, liver disease, sleep apnea or PCOS)
thus, the failed collateral pathway was fully recovered
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It signals the liver to release stored glucose by converting glycogen back into glucose, raising blood glucose levels
Stresses on the liver cause a feedback loop, where inflammation disrupts cell function