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Safety and efficacy data in pregnant populations remain under active investigation

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Constructs The native signal sequence (M1-P23) of human GLP-1R was replaced by the haemagglutinin (HA) signal peptide to facilitate receptor expression

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The plates were mixed using 1300 rpm (Heidolph Titramax 1000, #544-12200-00) and separated in the 96-well plate using a magnetic stand (Thermo Scientific, # AM10027)

Semaglutide: nonarteritic anterior ischemic optic neuropathy in the FDA adverse event reporting system: a disproportionality analysis