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Side effects and discontinuation rates matched other GLP-1 drugs

Studies have found that TMAO can significantly reduce the number of mitochondria, membrane potential, and ATP content of oocytes in polycystic ovary syndrome rat models, thus accelerating the apoptosis of oocytes

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A plaques originate from the aberrant processing of amyloid precursor protein (APP), mediated sequentially by - and -secretases

This mechanism ensures that insulin is released in response to elevated blood glucose levels, reducing the likelihood of hypoglycemic events

Table 1 Efficacy of GLP-1 agonists efficacy (adapted from UpToDate) ( GLP-1, glucagon-like peptide 1