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Discussion In summary, this study reports on the rational design, synthesis, and in-depth biological evaluation of tumor-targeting ruthenium containing nanoreactors for glutathione oxidation catalysis in osteosarcoma cells with a 1% O 2 atmosphere

PROTEOMICS 9 , 13851399 (2009)

An interesting therapeutic strategy is to induce arginine transporters (e.g., Slc7a2) in antitumor T cells, before their adoptive transfer to patients, enhancing their ability to compete for arginine in the TME, without the deleterious effects of arginine depletion for antitumor immunity [8]

10.3390/cancers11040510 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.van den Beuken-van Everdingen MHJ, Hochstenbach LMJ, Joosten EAJ, Tjan-Heijnen VCG, Janssen DJA

R., Pero, R