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Varicoceles can be identified on imaging, or palpated on physical examination

Eye 2011;25:767-774

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The reaction is a transamination in which the -amino group is transferred to the -keto carbon of 2-oxoglutarate (-ketoglutarate) forming the metabolite, saccharopine

El-Yazbi, Perirenal adipose tissue inflammation: novel insights linking metabolic dysfunction to renal diseases