It improves insulin sensitivity and reduces risk of gestational diabetes, lowers blood pressure and reduces preeclampsia risk, improves lipid profiles, reduces inflammation, enhances cardiovascular health, and decreases risks of pregnancy complications
If the myostatin inhibitor pipeline delivers if apitegromab or a successor can preserve not just lean mass but functional strength the combination of a GLP-1 drug (for systemic metabolic and anti-inflammatory effects) with a myostatin inhibitor (for muscle preservation) could become the first pharmacological intervention that addresses both the fat-accumulation and muscle-decline axes of aging simultaneously
Sleep and GLP-1 Side Effects Insufficient sleep does not just impact the effectiveness of GLP-1 medications
Beyond amyloid, emerging targets include tau, neuroinflammation and neurotransmitters
A clinician can help assess insomnia, medication effects, mood symptoms, pain, shift work, breathing problems during sleep, or withdrawal-related symptoms before any experimental approach enters the conversation
Endocrinology 145 : 46454652 Barazzoni R et al