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in vivo , while PC12 cells (treated with A25-35) were used to build an in vitro AD model

1.3.2 EHMT1 EHMT1 (also known as G9a-like protein (GLP)) is a histone methyltransferase that plays a key role in neurodevelopment by adding mono- and di-methyl groups to histone H3 at lysine 9 (H3K9me1/2), a modification associated with gene silencing and the regulation of chromatin structure (Padeken et al., 2022)