Department of Pharmacology and Therapeutics, Trinity College Dublin, Dublin, Ireland
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Curr Treat Options Cardiovasc Med
Subjects were studied using oral and iv glucose tolerance tests and acute administration of sitagliptin or placebo, in the presence or absence of iv exendin [939] (175)
Key findings from published experimental studies include characterisation of Tirzepatides receptor-binding kinetics, analysis of insulin secretion dynamics in isolated pancreatic beta-cell preparations, and observations of body composition changes in diet-induced obesity rodent models