Holly Lofton, M.D., professor of medicine and surgery at NYU Grossman School of Medicine and the director of the Medical Weight Management Program at NYU Langone Health in New York City
Koeth et al.: Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
Vitamin K2-7: Plays a crucial role in directing calcium into the bones and teeth, preventing its deposition in arteries and soft tissues
Phase 2 plannedPhase 2 initiation planned H1 2026 LonigutamabIGF-1R / subcutaneous humanized IgG1 monoclonal antibody / Endocrinology/ImmunologyThyroid eye diseaseDevelopment program evaluation ongoing IRF5/Additional TargetsIRF5, additional targetsUndisclosed 4assets AvexitideGLP-1 receptor / GLP-1 receptor antagonist / Endocrine/metabolic diseasesPost-bariatric hypoglycemia (PBH)Phase 3LUCIDITY completed enrollment
[Biochimie, 2014, vol
142 In addition, GLP-1 RA upregulated neurotrophic tyrosine kinase receptor type 2 and mTOR genes in the hippocampus of high-fat-fed mice, which are involved in regulating synaptic plasticity and LTP