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BMC Microbiol 23 , 187 (2023)

32 Supportive animal data suggest lifestyle modifications may promptly improve the epigenetic profile of the sperm within as little as three weeks, thus impacting health outcomes of offspring

The mechanisms driving these effects are multifaceted, involving the suppression of neuroinflammation via the TLR4/NF-B pathway and restoration of brain energy metabolism through the activation of the AMPK and SIRT1/GLUT4 signaling cascades (Wang et al., 2023

Semaglutide isnt recommended during pregnancy