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29,30 Insulin induces these effects by controlling the activity of the conserved TOR complex, 31 which transduces insulin signals to control cell growth, size, polarity and metabolism 3234 through its ability to sense prevailing nutrient and energy levels

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LPO products modulate the value of pro-inflammatory signaling through suppression of NF-B-dependent synthesis of pro-inflammatory cytokines and growth factors resulting in the prevention of inflammation-driven tumour formation [129]

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