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Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome

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Sulfasalazine combined with anti-IL-1 mAb induces ferroptosis and immune modulation in oral squamous cell carcinoma

However, some molecules or drugs, such as erastin, sulfasalazine, sorafenib, and RSL3, are able to block glutathione synthesis or devitalize GPX4

These cases are typically treated at home using gentle solutions that soothe irritation, itchiness, and redness

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