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FASEB J 28:18911897
Because large studies did not show robust, reproducible weightloss outcomes, development as a formal obesity drug was discontinued, and AOD9604 today is typically used offlabel as a wellness or bodycomposition adjunct rather than an FDAapproved obesity medication
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Finally, 5 clusters were obtained and two identified proteins of bifunctional dihydrofolate reductase-thymidylate (DRTS) and dihydrofolate synthase (folC) joint the network