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For the semaglutide 2.4-mg-containing groups, semaglutide was initiated at 0.25 mg once weekly for the first 4 weeks, with the dose increased to 0.5 mg from weeks 5 to 8, to 1.0 mg from weeks 9 to 12, to 1.7 mg from weeks 13 to 16 and to 2.4 mg from weeks 17 to 71

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Clinical studies help clarify the connection: In simple terms: the trigger is the speed of weight loss, not tirzepatide itself

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No tanning effect at any dose