Toxicon (2013) 71:6675
Practical Guidance If you choose to drink on a GLP-1 medication: Keep intake to 1 standard drink (5 oz wine, 12 oz beer, 1.5 oz spirits) maximum on any given day Never drink on an empty stomach pair alcohol with a protein-containing meal Drink water before, during, and after 1:1 ratio Never combine alcohol with insulin or sulfonylurea medications without extra caution Avoid sweetened cocktails (double impact: alcohol + sugar) Do not drink on the day of a dose increase side effects are worst that week The safest recommendation is to eliminate alcohol entirely during active weight loss on a GLP-1

| Electrolyte | Role in Body | Signs of Deficiency | Supplement Considerations ||-|||-|| Sodium | Fluid balance, nerve function | Lightheadedness, weakness, headache | May need increased intake during GLP-1 therapy || Potassium | Heart function, muscle control | Irregular heartbeat, muscle cramps | Monitor closely if on other medications || Magnesium | Muscle and nerve function | Fatigue, muscle twitches | Often depleted during weight loss || Calcium | Bone health, muscle function | Numbness, tingling | May need supplementation with vitamin D | Many patients dont realize that drinking excessive water without replenishing electrolytes can actually worsen lightheadedness symptoms, explains Dr
Research and expert guidance consistently emphasize that preserving muscle during weight loss supports strength, recovery, and long-term health
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