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A 2023 observational study found that patients on semaglutide reported significantly lower hunger during fasting periods compared to baseline, reducing the psychological burden of calorie restriction

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doi: 10.1002/oby.21244

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No significant difference was detected in demographic characteristics (ie, age, sex, race) between patients in the 2 groups

On one end are prescription injectables such as semaglutide (injectable) and tirzepatide (injectable), which have shown large average weight losses in high-quality trials