Absolute Cr concentration in the voxel (mean 6.09 IU) were also comparable to reported values
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however, in PD, the neurons producing dopamine slowly die out, causing an excess of acetylcholine to overstimulate the basal ganglia (Wang Q
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In rodents, modafinil, a wake-promoting drug that mediates dopamine-related psychostimulant action, prevented LPS-induced anxiety-like and depressive-like behaviors, as well as the LPS-induced increase in CD11b + CD45 high cells and IL-1 gene expression in the brain (Zager et al., 2018)