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By combining the physiological actions of amylin with structural modifications that enhance stability and extend half-life, cagrilintide represents a new therapeutic approach for chronic weight management and type 2 diabetes

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The same finding had been reported by a prior larger meta-analysis (6,914 patients with overweight or obesity and T2DM) over 8 studies 184,185,189,190,191,192,193,194 , but only when the largest study that also included non-diabetic participants 193 was excluded in a sensitivity analysis 195

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10.1124/dmd.105.009035PubMed Abstract | CrossRef Full Text | Google Scholar 98 MatsunagaN.KanekoN.StaubA