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reported a significant decrease in body weight and adipose tissue accumulation in these laboratory models following peptide exposure

Both compounds stimulate the pituitary to secrete more of the body's own GH rather than replacing itthis preserves hypothalamic-pituitary axis function and eliminates the weeks-long recovery period seen with synthetic GH cessation

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[6] [25] Additionally, these drugs suppress glucagon secretion (a hormone that raises blood glucose), slow gastric emptying to prolong satiety, and act on appetite centres in the brain to reduce food intake

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In the randomized controlled trial (RCT) by Kelly et al