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These beneficial effects may be due to the formation of detour circuitswhich encompass spared tissue surrounding the lesionand could reconnect locomotor circuits [69], thus enabling afferent inputs to be processed and conveyed to the cortex [73] and improving spinal reflexes, even below the injury [74]

The researchers used the TriNetX database a global health research network that aggregates deidentified data from more than 117 million people in the U.S

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"Overview of the Isoelectric Point (pI)"