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Another real-world study published in PMC examined patients with type 2 diabetes and confirmed that tirzepatide users had greater HbA1c and weight reductions at 12 months compared to injectable semaglutide users, regardless of whether they had previous GLP-1 receptor agonist experience

Doctors do know that GLP-1s appear to help curb hunger

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Serotonin transporter inhibition during neonatal period induces sex-dependent effects on mitochondrial bioenergetics in the rat brainstem