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Furthermore, in its bark has been determined that lupeol, acacetin phenylpropan hit acids, antioxidants and cytotoxic are responsible (Vilela et al., 2021)

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47 Even though there is heightened activity of glucouronidation and oxidative pathways, causing the increased clearance of APAP in pregnancy, no evidence exists to suggest pregnancy as a predisposing risk factor for APAP toxicity