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144152 Once in the intestinal lumen, UA can either be directly excreted or metabolized by the gut microbiota

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This phenomenon is particularly relevant in post-mitotic neurons, where caspase activation is often tightly controlled, yet sub-lethal mitochondrial permeabilization can still promote chronic inflammation

In studies involving patients with both alcoholic and non-alcoholic fatty liver disease, increasing glutathione levels was shown to reduce fat accumulation and significantly improve liver function

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