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Given that glutathione is a tripeptide composed of glutamate, glycine, and cysteine, glutamine-derived glutamate and cysteine need to be ligated by glutamate-cysteine ligase (GCL), which itself comprises two separately encoded proteins: a catalytic subunit (GCLC) and a modifier subunit (GCLM) 53,54
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In this work, we investigate various strategies for combining molecular representations and different model architectures with macroscopic p K a calculations, with the goal of finding a generally applicable aqueous-solubility-prediction method
Such pro-inflammatory macrophages accompany T cells in the inflamed joint, where both cell types compete for the access to glucose
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