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The highest epileptic seizure stage that each animal reached in 30-second intervals over the total analysis time (20 min) was recorded, and the latency to reach stage 4 and stage 5 of the seizure was also considered

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For example, intravenous administration of 1 g anserine to urethane-anesthetized rats suppressed the renal sympathetic nerve activity, blood pressure, and heart rate, whereas intravenous administration of 1 mg anserine had the opposite effects (Tanida et al