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R -lipoic acid is also found in the E3-binding protein (protein X component) of the pyruvate dehydrogenase complex (5)

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Biotransformation of some drugs are affected by acetylation rates, examples include hydralazine (Apresoline) and isoniazid (INH).: Pharmacogenetics: One major concern is that on underlying disease state may not be appreciated until an unexpected reaction to an anesthetic agent in fact occurs