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van Dooren FE, Nefs G, Schram MT, Verhey FR, Denollet J, Pouwer F

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there needs to be strong medical indications for any peptide's potential use

Similar results were observed in a study focusing on MC4R deficiency and pharmacotherapy [44] , where MC4R -deficient patients who underwent sleeve gastrectomy achieved stable short-term weight loss (mean 17.99% weight loss within 6 months), but long-term outcomes were heterogeneous and often accompanied by weight regain, requiring revisional surgery in some cases

The waistline definition improves

Mounjaro is initiated at a low dose (2.5 mg once weekly) and gradually increased at four-week intervals, allowing the body time to adjust to each increment