Nonetheless, residual effects on gastric emptying could still produce significant gastrointestinal adverse effects in patients treated with long-acting GLP-RAs (167)
Additionally, these agents improve pancreatic -cell function and become a means of achieving better long-term metabolic control, thereby making them a key part of modern approaches to diabetes management
Nagendra, L., Bg, H., Sharma, M
For instance, GLP-1RAs were demonstrated to reduce the risk of cardiovascular events (5) by decreasing the blood pressure (6), improving microvascular function, and reducing inflammation (7)
A Review and Meta-Analysis of the Safety and Efficacy of Using Glucagon-like Peptide-1 Receptor Agonists
The most serious side-effects, but which are rare, limit their use in persons having a history of pancreatis (inflammation of the pancreas) or thyroid cancer antecedents (due to the presence of GLP-1 receptors in the thyroid)