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This limits their real-world applicability and raises concerns regarding cost-effectiveness, safety profiling, and regulatory approval pathways

Disease spectrum and pathogenesis of NAFLD NAFLD encompasses a spectrum of hepatic disorders ranging from benign hepatic steatosis without inflammation to more severe conditions such as liver fibrosis and HCC

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Subanalyses of EXSCEL, SUSTAIN-6 and PIONEER-6 trials suggested that patients with HF may not necessarily benefit from GLP-1RA therapy

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A new study presented at a major cancer conference in Chicago suggests that possibility