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Glucagon-like peptide 1 (GLP-1) in the treatment of diabetes
In fact, there are several evidence-based weight loss treatments available right now, many with strong clinical data and real-world use behind them
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doi:10.1016/j.xops.2024.100547 23
There are also medical conditions where weight-loss drugs would not be recommended, including a history of medullary thyroid cancer, pancreatitis, gastroparesis, or a family history of MEN2 (multiple endocrine neoplasia syndrome type 2
Metabolic unpredictability: Simultaneously altering multiple metabolic pathways incretin signalling, glucagon activity, and NAD+ metabolism without clinical oversight introduces unpredictable physiological consequences
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