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Keywords: Anion gap, Acidosis, Paracetamol, Flucloxacillin, Interaction, 5-oxoproline Introduction Metabolic acidosis in patients admitted to the hospital is associated with morbidity and mortality

Across multiple disease areas, discussions increasingly focused not only on whether treatments work under controlled study conditions, but also on how they perform in diverse patient populations, how they impact quality of life, and how healthcare systems can generate evidence that supports more informed clinical, regulatory, and reimbursement decisions

ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion

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