In the United States, psoriasis affects approximately 7.4 million adults [1]
Importantly, as noted above, stem antibodies correlate both with resistance to infection and to severe disease in humans, indicating that this interesting mechanism is not predictive of disease causation for stem-specific antibodies 37
S., French S
Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain
For both Most Studied Pathways and Gene-Associated Pathways, the threshold of rank 30 was chosen to balance sensitivity and specificity, capturing pathways with substantial evidence while minimizing the inclusion of less relevant ones
The ectodomain of gp34 is sufficient to maintain Fc binding-mediated functions Despite the fact that gp34 is expressed as a type I transmembrane glycoprotein on the HCMV virion as well as infected cells, we found that membrane residency of gp34 is dispensable for the gp34-mediated abrogation of FcR activation (Corrales-Aguilar et al, 2014)
